Saturday July 4, 2020



August 24

Electronic Skin????

Traditional devices for sleep or heart monitoring include battery packs wired to large, inflexible sensors. This makes the units heavy, cumbersome, and a source of skin irritation. To create a chip that is as pliant as skin, John Rogers, an engineering professor at the University of Illinois at Urbana-Champaign, and colleagues created squiggly-shaped conductive gallium arsenide wires and mounted them on silicon that is less than 7 micrometers thick—two orders of magnitude thinner than a typical 500 micrometer silicon chip.


The combination of the thin silicon, the serpentine shape of the wires, and the layers of silicone and polyester in which the EES is mounted allow the chip to bend and stretch like skin without damaging the circuitry, according to the studypublished in Science (August 12).


August 23

Snoring and Wheezing in Children

Snoring is the most characteristic symptom of obstructive sleep-disordered breathing and recurrent wheezing is the most common clinical manifestation of asthma. Thus, taking under consideration the epidemiologic association between obstructive sleep-disordered breathing and asthma, when one of the two disorders is diagnosed, the possibility of the other disease being present should be entertained. 

Pediatr Pulmonol. 2011 Aug 1. doi: 10.1002/ppul.21497

August 21

FDA and generic development of Biological Agents such as Antibody Treatments

Senior officials at the US Food and Drug Administration laid out their guiding philosophy on regulating the production of generic versions of biological drugs such as antibodies, insulin or other proteins last Wednesday (August 3) in the New England Journal of Medicine.

Biologics generally have a more complicated production process than small molecule drugs, impeding the ability of generic manufacturers to prove they are producing an identical drug. Drug companies, therefore, have been eagerly awaiting guidance from the FDA as to what constitutes a sufficient level of “biosimilarity” to allow a generic version of a drug to be approved.

August 20

Need Lyme disease Antibodies - New Diagnostic Importance?

A recent report reflects that perhaps a different antibody may distinguish people who have active infection of Lyme disease from those that experience chronic, persistent symptoms of Lyme disease. Some people who are bitten by ticks and contract Lyme disease complain that their symptoms—including pain, lethargy, neurological problems and memory loss—persist for months or years after the infection has been treated with antibiotics. Controversy has swirled around such claims because physicians and researchers have been unable to find any trace of Borrelia burgdorferi, the spirochete bacterium that causes Lyme, in these so-called post-Lyme disease patients. In a research study, post-Lyme patients had developed a unique antibody response than in those who did not report chronic symptoms of the disease. This suggests that different antibody responses occurs in different patient populations. The research also opens the door to the possibility of a predictive biomarker that could help physicians identify Lyme patients at risk for developing the chronic form of the disease and treat them with more aggressive courses of antibiotics. Published in Nature News Published online 5 August 2011

Adult Deer Tick

August 19

Asthma and Maternal Mental Health

Maternal mental health may be a risk factor for the development of asthma and allergies in children, and a positive relationship has been found between concurrent maternal depression and childhood asthma. Also, mothers with anxiety during pregnancy were found to be more likely to have children with asthma by age 7 years.

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Today's Date: July 04, 2020
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